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MCE 国际站：L-Arginine
品牌：MedChemExpress (MCE)
CAS：74-79-3
纯度：0.9989
货号：HY-N0455
中文名称：L-精氨酸；L-蛋白氨基酸；L-胍基戊氨酸；L-2-氨基-胍基戊酸；2-氨基-5-胍基戊酸
Synonyms：L-精氨酸
存储条件：室温保存
运输条件：美国大陆的室温；其他地方可能有所不同。
产品活性：L-精氨酸 (L-Arginine) 是内皮型一氧化氮合酶 (eNOS) 产生 NO 的底物。L-Arginine 通过阳离子氨基酸转运体家族转运到血管平滑肌细胞，在那里它被代谢成一氧化氮 (NO)、多胺或 L-脯氨酸。L-Arginine 是有效的血管扩张剂，且可被用于诱导实验性急性胰腺炎。
IC50 & Target：Microbial Metabolite Human Endogenous Metabolite eNOS
热销产品：Hyaluronidase | G15 | Pemigatinib | (S)-Mephenytoin | Proteinase K | Sulfasalazine | Aspirin | PKM2-IN-1 | Auranofin | Indomethacin
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献：
[1]. Tapiero H, et al. I. Arginine. Biomed Pharmacother. 2002 Nov;56(9):439-45.
[2]. Bakker J, et al. Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients with severe sepsis: results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002). Crit Care Med. 2004 Jan;32(1):1-12.
[3]. Yamada M, et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab. 2000 Apr;20(4):709-17.[4]. Mizunuma T, et al. Effects of injecting excess arginine on rat pancreas. J Nutr. 1984 Mar;114(3):467-71.
[5]. Siriviriyakul P, et al. Effects of curcumin on oxidative stress, inflammation and apoptosis in L-arginine induced acute pancreatitis in mice. Heliyon. 2019 Aug 27;5(8):e02222.
