Abstract:
Objective
To explore whether PureRegen Gel Sinus is a suitable nasal packing material for patients with sleep-disordered breathing (SDB) caused by chronic rhinosinusitis plus nasal polys (CRSwNP).
Methods
A total of 216 CRSwNP cases including 156 SDB and 60 non-SDB cases were divided into 4 groups. Group A (60 non-SDB cases) and group B (56 SDB cases) were treated with PureRegen Gel Sinus after nasal sinus surgery. Group C included 47 SDB cases treated with Nasopore. Group D included 53 SDB cases treated with Medical Sponge. The nasal reactions of the 4 groups were compared with Visual Analogue Scale (VAS).
Results
There were significant differences in headache, rhinalgia and postoperative bleeding between group A and B (P<0.05). Patients with SDB were more intolerant to these complications. There were statistical differences in headache, rhinalgia, rhinobyon and lacrimation between group B and C (P<0.05). PureRegen Gel Sinus was was superior to Nasopore. There were statistical differences in headache, rhinalgia, rhinobyon, lacrimation, dysphagia and postoperative bleeding between group B and D (P<0.05). PureRegen Gel Sinus was no better than medical sponge in dealing with postoperative bleeding, but it was still acceptable. PureRegen Gel Sinus was superior to medical sponge in other aspects.
Conclusion
PureRegen Gel Sinus is more suitable for clinical practice as a packing material. In addition, SDB can worsen headache, rhinalgia and postoperative bleeding, which may be associated with inflammation resulted from long-term oxygen depletion.
